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CrcBiomeScreen

This is the development version of CrcBiomeScreen; for the stable release version, see CrcBiomeScreen.

All versions 3.24 (devel), 3.23 (release)

An R package for colorectal cancer screening and microbiome analysis


Bioconductor version: Development (3.24)

A developed and benchmarked reproducible machine learning framework for microbiome-based colorectal cancer (CRC) screening. By systematically evaluating normalization strategies, taxonomic resolutions, and class imbalance handling. This R package allows users to apply the full pipeline or selectively run specific components depending on their analytical needs. It establishes a scalable foundation for developing interpretable microbiome-based screening tools to support early CRC detection. This approach could be easily implemented in a national screening programme, to improve early detection rates for this disease.

Author: Chengxin Li [cre, aut] ORCID iD ORCID: 0009-0004-0840-9027 , Rishabh Bezbaruah [aut], Henry Wood [aut], Arief Gusnanto [aut]

Maintainer: Chengxin Li <ngzh5554 at leeds.ac.uk>

Citation (from within R, enter citation("CrcBiomeScreen")):

Chengxin Li, Rishabh Bezbaruah, Henry Wood, Arief Gusnanto. CrcBiomeScreen: An R package for colorectal cancer screening and microbiome analysis. doi:10.18129/B9.bioc.CrcBiomeScreen, R package version 1.1.6, https://bioconductor.org/packages/CrcBiomeScreen.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("CrcBiomeScreen")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CrcBiomeScreen")
CrcBiomeScreen HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews Classification, Metagenomics, Microbiome, Normalization, Software, Visualization
Version1.1.6
In Bioconductor sinceBioC 3.23 (R-4.6) (< 6 months)
License MIT + file LICENSE
Depends R (>= 4.3.0)
Imports rlang, methods, dplyr, doFuture, doParallel, foreach, future, future.apply, pROC, progress, progressr, stats, tibble, tidyr, TreeSummarizedExperiment, ggplot2, GUniFrac, magrittr, parallel, withr, SummarizedExperiment, caret, ranger, utils, graphics, grDevices
System Requirements
URLhttps://github.com/omicsForestry/CrcBiomeScreen
Bug Reportshttps://github.com/omicsForestry/CrcBiomeScreen/issues
See More
Suggests rstatix, MASS, mgcv, ggplotify, ggpubr, ggrepel, ggtree, glmnet, Matrix, microbiome, phyloseq, vegan, gt, testthat (>= 3.0.0), BiocManager, devtools, knitr, rmarkdown, BiocStyle, curatedMetagenomicData, xgboost
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package CrcBiomeScreen_1.1.6.tar.gz
Windows Binary (x86_64) CrcBiomeScreen_1.1.6.zip
macOS Binary (big-sur-x86_64) CrcBiomeScreen_1.1.6.tgz
macOS Binary (sonoma-arm64) CrcBiomeScreen_1.1.6.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/CrcBiomeScreen
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/CrcBiomeScreen
Package Short Url https://bioconductor.org/packages/CrcBiomeScreen/
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