Bioconductor Developer Survey 2026 Now Open!

ATACseqTFEA

This is the development version of ATACseqTFEA; for the stable release version, see ATACseqTFEA.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16

Transcription Factor Enrichment Analysis for ATAC-seq


Bioconductor version: Development (3.24)

Assay for Transpose-Accessible Chromatin using sequencing (ATAC-seq) is a technique to assess genome-wide chromatin accessibility by probing open chromatin with hyperactive mutant Tn5 Transposase that inserts sequencing adapters into open regions of the genome. ATACseqTFEA is an improvement of the current computational method that detects differential activity of transcription factors (TFs). ATACseqTFEA not only uses the difference of open region information, but also (or emphasizes) the difference of TFs footprints (cutting sites or insertion sites). ATACseqTFEA provides an easy, rigorous way to broadly assess TF activity changes between two conditions.

Author: Jianhong Ou [aut, cre] ORCID iD ORCID: 0000-0002-8652-2488

Maintainer: Jianhong Ou <jou at morgridge.org>

Citation (from within R, enter citation("ATACseqTFEA")):

Jianhong Ou. ATACseqTFEA: Transcription Factor Enrichment Analysis for ATAC-seq. doi:10.18129/B9.bioc.ATACseqTFEA, R package version 1.15.1, https://bioconductor.org/packages/ATACseqTFEA.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("ATACseqTFEA")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ATACseqTFEA")
ATACseqTFEA Vignette HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews ATACSeq, DNASeq, GeneRegulation, MNaseSeq, Sequencing, Software
Version1.15.1
In Bioconductor sinceBioC 3.16 (R-4.2) (4 years)
License GPL-3
Depends R (>= 4.2)
Imports BiocGenerics, cigarillo, S4Vectors, IRanges, Matrix, GenomicRanges, GenomicAlignments, Seqinfo, SummarizedExperiment, Rsamtools, motifmatchr, TFBSTools, stats, pracma, ggplot2, ggrepel, dplyr, limma, methods, rtracklayer
System Requirements
URLhttps://github.com/jianhong/ATACseqTFEA
Bug Reportshttps://github.com/jianhong/ATACseqTFEA/issues
See More
Suggests BSgenome.Drerio.UCSC.danRer10, knitr, testthat, ATACseqQC, rmarkdown, BiocStyle
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package ATACseqTFEA_1.15.1.tar.gz
Windows Binary (x86_64) ATACseqTFEA_1.15.1.zip
macOS Binary (big-sur-x86_64) ATACseqTFEA_1.15.1.tgz
macOS Binary (sonoma-arm64) ATACseqTFEA_1.15.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/ATACseqTFEA
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/ATACseqTFEA
Package Short Url https://bioconductor.org/packages/ATACseqTFEA/
Package Downloads ReportDownload Stats