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cogena

This is the released version of cogena; for the devel version, see cogena.

All Bioconductor versions of cogena

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1

co-expressed gene-set enrichment analysis

Bioconductor version: 3.23 · Package version: 1.46.0

cogena is a workflow for co-expressed gene-set enrichment analysis. It aims to discovery smaller scale, but highly correlated cellular events that may be of great biological relevance. A novel pipeline for drug discovery and drug repositioning based on the cogena workflow is proposed. Particularly, candidate drugs can be predicted based on the gene expression of disease-related data, or other similar drugs can be identified based on the gene expression of drug-related data. Moreover, the drug mode of action can be disclosed by the associated pathway analysis. In summary, cogena is a flexible workflow for various gene set enrichment analysis for co-expressed genes, with a focus on pathway/GO analysis and drug repositioning.

Author: Zhilong Jia [aut, cre], Michael Barnes [aut]

Maintainer: Zhilong Jia <zhilongjia at gmail.com>

DOI: 10.18129/B9.bioc.cogena

Citation

From within R, enter citation("cogena"):

Zhilong Jia, Michael Barnes. cogena: co-expressed gene-set enrichment analysis. doi:10.18129/B9.bioc.cogena, R package version 1.46.0, https://bioconductor.org/packages/cogena.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("cogena")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.46.0
LicenseLGPL-3
URLhttps://github.com/zhilongjia/cogena
Bug Reportshttps://github.com/zhilongjia/cogena/issues
Last updated2026-04-28
In Bioconductor sinceBioC 3.1 (R-3.2) (11 years)
Downloads rank594 of 2,418
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsClustering, DataImport, DataRepresentation, GO, GeneExpression, GeneSetEnrichment, KEGG, Microarray, Pathways, Sequencing, Software, SystemsBiology, Visualization
Package Short Url https://bioconductor.org/packages/cogena/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("cogena")
a workflow of cogena HTML R Script
cogena, a workflow for gene set enrichment analysis of co-expressed genes HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packagecogena_1.46.0.tar.gz
Windows binary (x86_64)cogena_1.46.0.zip
macOS binary (arm64)cogena_1.46.0.tgz
macOS binary (x86_64)cogena_1.46.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/cogena
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/cogena
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 3.6), cluster, ggplot2, kohonen

Imports: methods, class, gplots, mclust, amap, apcluster, foreach, parallel, doParallel, fastcluster, corrplot, biwt, Biobase, reshape2, stringr, tibble, tidyr, dplyr, devtools

Suggests: knitr, rmarkdown (>= 2.1)