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atacInferCnv

This is the released version of atacInferCnv; for the devel version, see atacInferCnv.

Call CNV from single cell ATAC-seq data based on InferCNV adaptation


Bioconductor version: Release (3.23)

The package prepares input scATAC-seq data and adapts for copy number variance profiling with InferCNV package usage. It has also various paramters to control the analysis (e.g. external normal reference usage, meta-cells, bin size, etc) and custom plot visualizations.

Author: Konstantin Okonechnikov [aut, cre] ORCID iD ORCID: 0000-0002-3409-2340 , Supat Thongjuea [aut, fnd]

Maintainer: Konstantin Okonechnikov <k.okonechnikov at gmail.com>

Citation (from within R, enter citation("atacInferCnv")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("atacInferCnv")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("atacInferCnv")
atacInferCnv: CNV inference from scATAC-seq data HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews CopyNumberVariation, Epigenetics, ImmunoOncology, Sequencing, SingleCell, Software
Version 1.0.0
In Bioconductor since BioC 3.23 (R-4.6) (< 6 months)
License GPL-3 + file LICENSE
Depends R (>= 4.6.0), utils
Imports infercnv(>= 1.3.1), Signac, Seurat, GenomicRanges, GenomeInfoDb, S4Vectors, config, stringr, ggplot2, SummarizedExperiment, SingleCellExperiment, Rcpp
System Requirements
URL https://github.com/kokonech/atacInferCNV
Bug Reports https://github.com/kokonech/atacInferCNV/issues
See More
Suggests testthat (>= 3.0.0), BiocStyle, knitr, rmarkdown
Linking To Rcpp, RcppEigen
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package atacInferCnv_1.0.0.tar.gz
Windows Binary (x86_64)
macOS Binary (big-sur-x86_64) atacInferCnv_1.0.0.tgz
macOS Binary (sonoma-arm64) atacInferCnv_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/atacInferCnv
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/atacInferCnv
Bioc Package Browser https://code.bioconductor.org/browse/atacInferCnv/
Package Short Url https://bioconductor.org/packages/atacInferCnv/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.23 Source Archive