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Seqtometry

This is the released version of Seqtometry; for the devel version, see Seqtometry.

All versions 3.24 (devel), 3.23 (release)

Signature scoring for single cell analysis


Bioconductor version: Release (3.23)

This package provides functions used in Seqtometry (Kousnetsov et al. 2024), a method for analyzing single cell (scRNA-seq or scATAC-seq) data via signature (gene set) enrichment scores. The Seqtometry scores may be useful for annotating or characterizing cells, either in a flow cytometry like workflow (where scores are standalone features used for progressive partitoning as described in the Seqtometry publication) or in a cluster-based workflow (as features of clusters). The exported impute function (a port of Python's MAGIC-impute, van Dijk et al. 2018), may also be useful for single cell analysis on its own.

Author: Robert Kousnetsov [aut, cre], Daniel Hawiger [cph, fnd]

Maintainer: Robert Kousnetsov <robert.kousnetsov at health.slu.edu>

Citation (from within R, enter citation("Seqtometry")):

Robert Kousnetsov. Seqtometry: Signature scoring for single cell analysis. doi:10.18129/B9.bioc.Seqtometry, R package version 1.0.1, https://bioconductor.org/packages/Seqtometry.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Seqtometry")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("Seqtometry")
Seqtometry vignette HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews GeneExpression, GeneSetEnrichment, SingleCell, Software
Version1.0.1
In Bioconductor sinceBioC 3.23 (R-4.6) (< 6 months)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports BiocSingular, checkmate, data.table, DelayedMatrixStats, future.apply, Matrix, MatrixGenerics, purrr, Rcpp, RcppHNSW, RSpectra, sparseMatrixStats, zeallot
System Requirements
URLhttps://github.com/HawigerLab/Seqtometry
Bug Reportshttps://github.com/HawigerLab/Seqtometry/issues
See More
Suggests BiocStyle, box, dplyr, future, ggplot2, harmony, knitr, MASS, patchwork, rmarkdown, scater, scuttle, SingleCellExperiment, stringr, TENxPBMCData, testthat (>= 3.0.0), tibble
Linking To Rcpp, RcppArmadillo
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package Seqtometry_1.0.1.tar.gz
Windows Binary (x86_64) Seqtometry_1.0.1.zip
macOS Binary (big-sur-x86_64) Seqtometry_1.0.1.tgz
macOS Binary (sonoma-arm64) Seqtometry_1.0.1.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/Seqtometry
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/Seqtometry
Package Short Url https://bioconductor.org/packages/Seqtometry/
Package Downloads ReportDownload Stats
Old Source Packages for BioC 3.23Source Archive