RolDE

RolDE: Robust longitudinal Differential Expression


Bioconductor version: Release (3.19)

RolDE detects longitudinal differential expression between two conditions in noisy high-troughput data. Suitable even for data with a moderate amount of missing values.RolDE is a composite method, consisting of three independent modules with different approaches to detecting longitudinal differential expression. The combination of these diverse modules allows RolDE to robustly detect varying differences in longitudinal trends and expression levels in diverse data types and experimental settings.

Author: Tommi Valikangas [aut], Medical Bioinformatics Centre [cre]

Maintainer: Medical Bioinformatics Centre <mbc at utu.fi>

Citation (from within R, enter citation("RolDE")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("RolDE")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RolDE")
Introduction HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews DifferentialExpression, Proteomics, Regression, Software, StatisticalMethod, TimeCourse
Version 1.8.0
In Bioconductor since BioC 3.15 (R-4.2) (2.5 years)
License GPL-3
Depends R (>= 4.2.0)
Imports stats, methods, ROTS, matrixStats, foreach, parallel, doParallel, doRNG, rngtools, SummarizedExperiment, nlme, qvalue, grDevices, graphics, utils
System Requirements
URL https://github.com/elolab/RolDE
Bug Reports https://github.com/elolab/RolDE/issues
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Suggests knitr, printr, rmarkdown, testthat
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package RolDE_1.8.0.tar.gz
Windows Binary RolDE_1.8.0.zip
macOS Binary (x86_64) RolDE_1.8.0.tgz
macOS Binary (arm64) RolDE_1.8.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/RolDE
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/RolDE
Bioc Package Browser https://code.bioconductor.org/browse/RolDE/
Package Short Url https://bioconductor.org/packages/RolDE/
Package Downloads Report Download Stats