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MPRAnalyze

This is the released version of MPRAnalyze; for the devel version, see MPRAnalyze.

All Bioconductor versions of MPRAnalyze

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8

Statistical Analysis of MPRA data

Bioconductor version: 3.23 · Package version: 1.30.0

MPRAnalyze provides statistical framework for the analysis of data generated by Massively Parallel Reporter Assays (MPRAs), used to directly measure enhancer activity. MPRAnalyze can be used for quantification of enhancer activity, classification of active enhancers and comparative analyses of enhancer activity between conditions. MPRAnalyze construct a nested pair of generalized linear models (GLMs) to relate the DNA and RNA observations, easily adjustable to various experimental designs and conditions, and provides a set of rigorous statistical testig schemes.

Author: Tal Ashuach [aut, cre], David S Fischer [aut], Anat Kriemer [ctb], Fabian J Theis [ctb], Nir Yosef [ctb],

Maintainer: Tal Ashuach <tal_ashuach at berkeley.edu>

DOI: 10.18129/B9.bioc.MPRAnalyze

Citation

From within R, enter citation("MPRAnalyze"):

Tal Ashuach, David S Fischer. MPRAnalyze: Statistical Analysis of MPRA data. doi:10.18129/B9.bioc.MPRAnalyze, R package version 1.30.0, https://bioconductor.org/packages/MPRAnalyze.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("MPRAnalyze")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.30.0
LicenseGPL-3
URLhttps://github.com/YosefLab/MPRAnalyze
Bug Reportshttps://github.com/YosefLab/MPRAnalyze
Last updated2026-04-28
In Bioconductor sinceBioC 3.8 (R-3.5) (7 years)
Downloads rank1575 of 2,418
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsCellBasedAssays, CellBiology, Classification, DifferentialExpression, ExperimentalDesign, GeneExpression, ImmunoOncology, Sequencing, Software, StatisticalMethod
Package Short Url https://bioconductor.org/packages/MPRAnalyze/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MPRAnalyze")
Analyzing MPRA data with MPRAnalyze HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packageMPRAnalyze_1.30.0.tar.gz
Windows binary (x86_64)MPRAnalyze_1.30.0.zip
macOS binary (arm64)MPRAnalyze_1.30.0.tgz
macOS binary (x86_64)MPRAnalyze_1.30.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/MPRAnalyze
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/MPRAnalyze
Package Downloads ReportDownload Stats
Dependencies

Imports: BiocParallel, methods, progress, stats, SummarizedExperiment

Suggests: knitr