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CTCF

This is the released version of CTCF; for the devel version, see CTCF.

All Bioconductor versions of CTCF

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14

Genomic coordinates of CTCF binding sites, with orientation

Bioconductor version: 3.23 · Package version: 0.99.14

Genomic coordinates of CTCF binding sites, with strand orientation (directionality of binding). Position weight matrices (PWMs) from JASPAR, HOCOMOCO, CIS-BP, CTCFBSDB, SwissRegulon, Jolma 2013, were used to uniformly predict CTCF binding sites using FIMO (default settings) on human (hg18, hg19, hg38, T2T) and mouse (mm9, mm10, mm39) genome assemblies. Extra columns include motif/PWM name (e.g., MA0139.1), score, p-value, q-value, and the motif sequence. It is recommended to filter FIMO-predicted sites by 1e-6 p-value threshold instead of using the default 1e-4 threshold. Experimentally obtained CTCF-bound cis-regulatory elements from ENCODE SCREEN and predicted CTCF sites from CTCFBSDB are also included. Selected data are lifted over from a different genome assembly as we demonstrated liftOver is a viable option to obtain CTCF coordinates in different genome assemblies. CTCF sites obtained using JASPAR's MA0139.1 PWM and filtered at 1e-6 p-value threshold are recommended.

Author: Mikhail Dozmorov [aut, cre] ORCID iD ORCID: 0000-0002-0086-8358 , Eric Davis [aut], Wancen Mu [aut], Stuart Lee [aut], Tim Triche [aut], Douglas Phanstiel [aut], Michael Love [aut]

Maintainer: Mikhail Dozmorov <mikhail.dozmorov at gmail.com>

DOI: 10.18129/B9.bioc.CTCF

Citation

From within R, enter citation("CTCF"):

Mikhail Dozmorov, Eric Davis, Wancen Mu, Stuart Lee, Tim Triche, Douglas Phanstiel, Michael Love. CTCF: Genomic coordinates of CTCF binding sites, with orientation. doi:10.18129/B9.bioc.CTCF, R package version 0.99.14, https://bioconductor.org/packages/CTCF.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CTCF")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version0.99.14
LicenseMIT + file LICENSE
URLhttps://github.com/dozmorovlab/CTCF
Bug Reportshttps://github.com/dozmorovlab/CTCF/issues
Last updated2026-01-07
In Bioconductor sinceBioC 3.14 (R-4.1) (4 years)
Downloads rank531 of 928
Source branchRELEASE_3_23
biocViewsAnnotationData, AnnotationHub, FunctionalAnnotation, GenomicSequence
Package Short Url https://bioconductor.org/packages/CTCF/

Documentation

Reference ManualPDF

Download

Follow the installation instructions to use this package in your R session.

Source packageCTCF_0.99.14.tar.gz
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Dependencies

Suggests: BiocStyle, rmarkdown, knitr, GenomeInfoDb, AnnotationHub, GenomicRanges, sessioninfo