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CPSM

This is the released version of CPSM; for the devel version, see CPSM.

CPSM: Cancer patient survival model


Bioconductor version: Release (3.23)

CPSM provides a comprehensive computational pipeline for predicting survival probability and risk groups in cancer patients. The package includes steps for data preprocessing, training/test split, and normalization. It enables feature selection using univariate survival analysis and computes a LASSO-based prognostic index (PI) score. CPSM supports the development of predictive models using various feature sets and offers a suite of visualization tools, including survival curves based on predicted probabilities, barplots for predicted mean and median survival times, KM plots overlaid with individual survival predictions, and nomograms for estimating 1-, 3-, 5-, and 10-year survival probabilities. This makes CPSM a versatile tool for survival analysis in cancer research.

Author: Harpreet Kaur [aut, cre] ORCID iD ORCID: 0000-0003-0421-8341 , Pijush Das [aut], Kevin Camphausen [aut], Uma Shankavaram [aut, ctb]

Maintainer: Harpreet Kaur <hks04180 at gmail.com>

Citation (from within R, enter citation("CPSM")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CPSM")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CPSM")
CPSM: Cancer patient survival model HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews FeatureExtraction, GeneExpression, Normalization, Preprocessing, Software, Survival, Visualization
Version 1.4.0
In Bioconductor since BioC 3.21 (R-4.5) (1.5 years)
License GPL-3 | file LICENSE
Depends R (>= 4.5)
Imports SummarizedExperiment, grDevices, reshape2, survival, survminer, ggplot2, MTLR, glmnet, rms, preprocessCore, Matrix, stats, Hmisc, ggfortify, randomForestSRC, caret, SurvMetrics, MASS
System Requirements
URL https://github.com/hks5august/CPSM/
Bug Reports https://github.com/hks5august/CPSM/issues
See More
Suggests knitr, rmarkdown, testthat (>= 3.0.0), BiocStyle
Linking To
Enhances
Depends On Me
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Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package CPSM_1.4.0.tar.gz
Windows Binary (x86_64) CPSM_1.4.0.zip
macOS Binary (big-sur-x86_64) CPSM_1.4.0.tgz
macOS Binary (sonoma-arm64) CPSM_1.4.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/CPSM
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/CPSM
Bioc Package Browser https://code.bioconductor.org/browse/CPSM/
Package Short Url https://bioconductor.org/packages/CPSM/
Package Downloads Report Download Stats