Bioconductor Developer Survey 2026 Now Open!

CIMICE

This is the released version of CIMICE; for the devel version, see CIMICE.

All Bioconductor versions of CIMICE

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13

CIMICE-R: (Markov) Chain Method to Inferr Cancer Evolution

Bioconductor version: 3.23 · Package version: 1.20.0

CIMICE is a tool in the field of tumor phylogenetics and its goal is to build a Markov Chain (called Cancer Progression Markov Chain, CPMC) in order to model tumor subtypes evolution. The input of CIMICE is a Mutational Matrix, so a boolean matrix representing altered genes in a collection of samples. These samples are assumed to be obtained with single-cell DNA analysis techniques and the tool is specifically written to use the peculiarities of this data for the CMPC construction.

Author: Nicolò Rossi [aut, cre] (Lab. of Computational Biology and Bioinformatics, Department of Mathematics, Computer Science and Physics, University of Udine, ORCID: ORCID iD ORCID: 0000-0002-6353-7396 )

Maintainer: Nicolò Rossi <olocin.issor at gmail.com>

DOI: 10.18129/B9.bioc.CIMICE

Citation

From within R, enter citation("CIMICE"):

Nicolò Rossi. CIMICE: CIMICE-R: (Markov) Chain Method to Inferr Cancer Evolution. doi:10.18129/B9.bioc.CIMICE, R package version 1.20.0, https://bioconductor.org/packages/CIMICE.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CIMICE")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.20.0
LicenseArtistic-2.0
URLhttps://github.com/redsnic/CIMICE
Bug Reportshttps://github.com/redsnic/CIMICE/issues
Last updated2026-04-28
In Bioconductor sinceBioC 3.13 (R-4.1) (5 years)
Downloads rank1830 of 2,418
Source branchRELEASE_3_23
Build report Bioconductor build system, r-universe
biocViewsBiologicalQuestion, GraphAndNetwork, NetworkInference, Phylogenetics, ResearchField, SingleCell, Software, StatisticalMethod, Technology
Package Short Url https://bioconductor.org/packages/CIMICE/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CIMICE")
CIMICE-R: (Markov) Chain Method to Infer Cancer Evolution HTML R Script
Quick guide HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packageCIMICE_1.20.0.tar.gz
Windows binary (x86_64)CIMICE_1.20.0.zip
macOS binary (arm64)CIMICE_1.20.0.tgz
macOS binary (x86_64)CIMICE_1.20.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/CIMICE
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/CIMICE
Package Downloads ReportDownload Stats
Dependencies

Imports: dplyr, ggplot2, glue, tidyr, igraph, networkD3, visNetwork, ggcorrplot, purrr, ggraph, stats, utils, maftools, assertthat, tidygraph, expm, Matrix

Suggests: BiocStyle, knitr, rmarkdown, testthat, webshot