DOI: 10.18129/B9.bioc.TBSignatureProfiler    

This is the development version of TBSignatureProfiler; for the stable release version, see TBSignatureProfiler.

Profile RNA-Seq Data Using TB Pathway Signatures

Bioconductor version: Development (3.13)

Signatures of TB progression, TB disease, and other TB disease states have been created. This package makes it easy to profile RNA-Seq data using these signatures and common signature profiling tools including ASSIGN, GSVA, and ssGSEA.

Author: David Jenkins <dfj at bu.edu>, Aubrey Odom <aodom at bu.edu>, Yue Zhao <yuezh at bu.edu>, W. Evan Johnson <wej at bu.edu>, Christian Love <clove at bu.edu>

Maintainer: Aubrey Odom <aodom at bu.edu>

Citation (from within R, enter citation("TBSignatureProfiler")):


To install this package, start R (version "4.1") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


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biocViews DifferentialExpression, GeneExpression, Software
Version 1.3.5
In Bioconductor since BioC 3.11 (R-4.0) (1 year)
License MIT + file LICENSE
Depends R (>= 4.0.0)
Imports ASSIGN(>= 1.23.1), GSVA, singscore, methods, ComplexHeatmap, RColorBrewer, ggplot2, S4Vectors, reshape2, ROCit, DESeq2, DT, edgeR, gdata, SummarizedExperiment, magrittr, stats, rlang, BiocParallel, BiocGenerics
Suggests testthat, spelling, lintr, covr, knitr, rmarkdown, BiocStyle, shiny, circlize, caret, dplyr, plyr, impute, sva, glmnet, randomForest, MASS, class, e1071, pROC
URL https://github.com/compbiomed/TBSignatureProfiler
BugReports https://github.com/compbiomed/TBSignatureProfiler/issues
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Source Repository git clone https://git.bioconductor.org/packages/TBSignatureProfiler
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/TBSignatureProfiler
Package Short Url https://bioconductor.org/packages/TBSignatureProfiler/
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