DOI: 10.18129/B9.bioc.TargetScore    

This is the development version of TargetScore; for the stable release version, see TargetScore.

TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information

Bioconductor version: Development (3.8)

Infer the posterior distributions of microRNA targets by probabilistically modelling the likelihood microRNA-overexpression fold-changes and sequence-based scores. Variaitonal Bayesian Gaussian mixture model (VB-GMM) is applied to log fold-changes and sequence scores to obtain the posteriors of latent variable being the miRNA targets. The final targetScore is computed as the sigmoid-transformed fold-change weighted by the averaged posteriors of target components over all of the features.

Author: Yue Li

Maintainer: Yue Li <yueli at>

Citation (from within R, enter citation("TargetScore")):


To install this package, start R and enter:

if (!requireNamespace("BiocManager", quietly=TRUE))
BiocManager::install("TargetScore", version = "devel")


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PDF R Script TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information
PDF   Reference Manual
Text   NEWS


biocViews Software, miRNA
Version 1.19.0
In Bioconductor since BioC 2.13 (R-3.0) (5 years)
License GPL-2
Depends pracma, Matrix
Suggests TargetScoreData, gplots, Biobase, GEOquery
Depends On Me
Imports Me
Suggests Me TargetScoreData
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