To install this package, start R and enter:

source("http://bioconductor.org/biocLite.R")
biocLite("TargetScore")

In most cases, you don't need to download the package archive at all.

TargetScore

TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information

Bioconductor version: Release (2.14)

Infer the posterior distributions of microRNA targets by probabilistically modelling the likelihood microRNA-overexpression fold-changes and sequence-based scores. Variaitonal Bayesian Gaussian mixture model (VB-GMM) is applied to log fold-changes and sequence scores to obtain the posteriors of latent variable being the miRNA targets. The final targetScore is computed as the sigmoid-transformed fold-change weighted by the averaged posteriors of target components over all of the features.

Author: Yue Li

Maintainer: Yue Li <yueli at cs.toronto.edu>

Citation (from within R, enter citation("TargetScore")):

Installation

To install this package, start R and enter:

source("http://bioconductor.org/biocLite.R")
biocLite("TargetScore")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("TargetScore")

 

PDF R Script TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information
PDF   Reference Manual
Text   NEWS

Details

biocViews Software, miRNA
Version 1.2.0
In Bioconductor since BioC 2.13 (R-3.0)
License GPL-2
Depends pracma, Matrix
Imports
Suggests TargetScoreData, gplots, Biobase, GEOquery
System Requirements
URL http://www.cs.utoronto.ca/~yueli/software.html
Depends On Me
Imports Me
Suggests Me TargetScoreData

Package Archives

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Package Source TargetScore_1.2.0.tar.gz
Windows Binary TargetScore_1.2.0.zip (32- & 64-bit)
Mac OS X 10.6 (Snow Leopard) TargetScore_1.2.0.tgz
Mac OS X 10.9 (Mavericks) TargetScore_1.2.0.tgz
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