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trio

 

   

This is the development version of trio; for the stable release version, see trio.

Testing of SNPs and SNP Interactions in Case-Parent Trio Studies

Bioconductor version: Development (3.3)

Testing SNPs and SNP interactions with a genotypic TDT. This package furthermore contains functions for computing pairwise values of LD measures and for identifying LD blocks, as well as functions for setting up matched case pseudo-control genotype data for case-parent trios in order to run trio logic regression, for imputing missing genotypes in trios, for simulating case-parent trios with disease risk dependent on SNP interaction, and for power and sample size calculation in trio data.

Author: Holger Schwender, Qing Li, Philipp Berger, Christoph Neumann, Margaret Taub, Ingo Ruczinski

Maintainer: Holger Schwender <holger.schw at gmx.de>

Citation (from within R, enter citation("trio")):

Installation

To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("trio")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("trio")

 

PDF Trio Logic Regression and genotypic TDT
PDF   Reference Manual

Details

biocViews GeneticVariability, Genetics, Microarray, SNP, Software
Version 3.9.1
In Bioconductor since BioC 2.13 (R-3.0) (2.5 years)
License LGPL-2
Depends R (>= 3.0.1)
Imports
LinkingTo
Suggests survival, haplo.stats, mcbiopi, siggenes, splines, LogicReg (>= 1.5.3), logicFS(>= 1.28.1), KernSmooth, VariantAnnotation
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Package Source trio_3.9.1.tar.gz
Windows Binary trio_3.9.1.zip
Mac OS X 10.6 (Snow Leopard) trio_3.7.1.tgz
Mac OS X 10.9 (Mavericks) trio_3.9.1.tgz
Subversion source (username/password: readonly)
Git source https://github.com/Bioconductor-mirror/trio
Package Short Url http://bioconductor.org/packages/trio/
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