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shinyepico

This is the released version of shinyepico; for the devel version, see shinyepico.

ShinyÉPICo


Bioconductor version: Release (3.23)

ShinyÉPICo is a graphical pipeline to analyze Illumina DNA methylation arrays (450k or EPIC). It allows to calculate differentially methylated positions and differentially methylated regions in a user-friendly interface. Moreover, it includes several options to export the results and obtain files to perform downstream analysis.

Author: Octavio Morante-Palacios [cre, aut]

Maintainer: Octavio Morante-Palacios <octaviompa at gmail.com>

Citation (from within R, enter citation("shinyepico")):
Seminal Bioconductor project articles:

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M (2015). "Orchestrating high-throughput genomic analysis with Bioconductor." Nature Methods, 12(2), 115–121. doi:10.1038/nmeth.3252.

Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JYH, Zhang J (2004). "Bioconductor: open software development for computational biology and bioinformatics." Genome Biology, 5(10), R80. doi:10.1186/gb-2004-5-10-r80.

Installation

To install this package, start R (version "4.6") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("shinyepico")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("shinyepico")
shinyepico HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews DNAMethylation, DifferentialMethylation, Microarray, Preprocessing, QualityControl, Software
Version 1.20.0
In Bioconductor since BioC 3.13 (R-4.1) (5 years)
License AGPL-3 + file LICENSE
Depends R (>= 4.3.0)
Imports DT (>= 0.15.0), data.table (>= 1.13.0), doParallel (>= 1.0.0), dplyr (>= 1.0.9), foreach (>= 1.5.0), GenomicRanges(>= 1.38.0), ggplot2 (>= 3.3.0), gplots (>= 3.0.0), heatmaply (>= 1.1.0), limma(>= 3.42.0), minfi(>= 1.32.0), plotly (>= 4.9.2), reshape2 (>= 1.4.0), rlang (>= 1.0.2), rmarkdown (>= 2.3.0), rtracklayer(>= 1.46.0), shiny (>= 1.5.0), shinyWidgets (>= 0.5.0), shinycssloaders (>= 0.3.0), shinyjs (>= 1.1.0), shinythemes (>= 1.1.0), statmod (>= 1.4.0), tidyr (>= 1.2.0), zip (>= 2.1.0)
System Requirements
URL https://github.com/omorante/shiny_epico
Bug Reports https://github.com/omorante/shiny_epico/issues
See More
Suggests knitr (>= 1.30.0), mCSEA(>= 1.10.0), IlluminaHumanMethylation450kanno.ilmn12.hg19, IlluminaHumanMethylation450kmanifest, IlluminaHumanMethylationEPICanno.ilm10b4.hg19, IlluminaHumanMethylationEPICmanifest, testthat, minfiData, BiocStyle
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package shinyepico_1.20.0.tar.gz
Windows Binary (x86_64) shinyepico_1.20.0.zip (64-bit only)
macOS Binary (big-sur-x86_64) shinyepico_1.20.0.tgz
macOS Binary (sonoma-arm64) shinyepico_1.20.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/shinyepico
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/shinyepico
Bioc Package Browser https://code.bioconductor.org/browse/shinyepico/
Package Short Url https://bioconductor.org/packages/shinyepico/
Package Downloads Report Download Stats