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DEXSeq

This is the released version of DEXSeq; for the devel version, see DEXSeq.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4, 3.3, 3.2, 3.1, 3.0, 2.14, 2.13, 2.12, 2.11, 2.10, 2.9

Inference of differential exon usage in RNA-Seq


Bioconductor version: Release (3.23)

The package is focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results.

Author: Simon Anders [aut], Alejandro Reyes [aut, ccp] (Maintainer until 2026.), Hugo Gruson [cre]

Maintainer: Hugo Gruson <hugo.gruson at embl.de>

Citation (from within R, enter citation("DEXSeq")):

Simon Anders, Alejandro Reyes. DEXSeq: Inference of differential exon usage in RNA-Seq. doi:10.18129/B9.bioc.DEXSeq, R package version 1.58.0, https://bioconductor.org/packages/DEXSeq.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DEXSeq")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DEXSeq")
Inferring differential exon usage in RNA-Seq data with the DEXSeq package HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews AlternativeSplicing, DifferentialExpression, DifferentialSplicing, GeneExpression, ImmunoOncology, RNASeq, Sequencing, Software, Visualization
Version1.58.0
In Bioconductor sinceBioC 2.9 (R-2.14) (15 years)
License GPL (>= 3)
Depends BiocParallel, Biobase, SummarizedExperiment, IRanges (>= 2.5.17), GenomicRanges (>= 1.23.7), DESeq2 (>= 1.39.6), AnnotationDbi, S4Vectors (>= 0.23.18)
Imports BiocGenerics, biomaRt, hwriter, methods, stringr, Rsamtools, statmod, geneplotter, genefilter
System Requirements
URL
See More
Suggests GenomeInfoDb, GenomicFeatures, txdbmaker, pasilla (>= 0.2.22), BiocStyle, knitr, rmarkdown, testthat, pasillaBamSubset, GenomicAlignments, roxygen2, glmGamPoi
Linking To
Enhances
Depends On Me IsoformSwitchAnalyzeR, pasilla, rnaseqDTU
Imports Me diffUTR, IntEREst, pairedGSEA
Suggests Me bambu, BioPlex, GenomicRanges, satuRn, stageR, subSeq
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DEXSeq_1.58.0.tar.gz
Windows Binary (x86_64) DEXSeq_1.58.0.zip
macOS Binary (big-sur-x86_64) DEXSeq_1.58.0.tgz
macOS Binary (sonoma-arm64) DEXSeq_1.58.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/DEXSeq
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/DEXSeq
Package Short Url https://bioconductor.org/packages/DEXSeq/
Package Downloads ReportDownload Stats