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Adaptive Signature Selection and InteGratioN (ASSIGN)

Bioconductor version: Release (3.0)

ASSIGN is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway signatures derived either from knowledge-based literatures or from perturbation experiments to the cell-/tissue-specific pathway signatures. The deregulation/activation level of each context-specific pathway is quantified to a score, which represents the extent to which a patient sample encompasses the pathway deregulation/activation signature.

Author: Ying Shen, Andrea H. Bild, and W. Evan Johnson

Maintainer: Ying Shen <yshen3 at>

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biocViews Bayesian, GeneExpression, Pathways, Software
Version 1.2.0
In Bioconductor since BioC 2.14 (R-3.1)
License MIT
Depends Rlab, msm, gplots
Imports graphics, grDevices, stats, utils
Depends On Me
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