lefser

R implementation of the LEfSE method for microbiome biomarker discovery


Bioconductor version: Release (3.20)

lefser is the R implementation of the popular microbiome biomarker discovery too, LEfSe. It uses the Kruskal-Wallis test, Wilcoxon-Rank Sum test, and Linear Discriminant Analysis to find biomarkers from two-level classes (and optional sub-classes).

Author: Sehyun Oh [cre, ctb] , Asya Khleborodova [aut], Samuel Gamboa-Tuz [ctb], Marcel Ramos [ctb] , Ludwig Geistlinger [ctb] , Levi Waldron [ctb]

Maintainer: Sehyun Oh <shbrief at gmail.com>

Citation (from within R, enter citation("lefser")):

Installation

To install this package, start R (version "4.4") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("lefser")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("lefser")
Quickstart HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Classification, DifferentialExpression, Microbiome, Sequencing, Software, StatisticalMethod
Version 1.16.0
In Bioconductor since BioC 3.12 (R-4.0) (4 years)
License Artistic-2.0
Depends SummarizedExperiment, R (>= 4.0.0)
Imports coin, MASS, ggplot2, S4Vectors, stats, methods, utils, dplyr, testthat, tibble, tidyr, forcats, stringr, ggtree
System Requirements
URL https://github.com/waldronlab/lefser
Bug Reports https://github.com/waldronlab/lefser/issues
See More
Suggests knitr, rmarkdown, curatedMetagenomicData, BiocStyle, phyloseq, pkgdown, covr, withr
Linking To
Enhances
Depends On Me
Imports Me ggpicrust2
Suggests Me dar
Links To Me
Build Report Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package lefser_1.16.0.tar.gz
Windows Binary (x86_64) lefser_1.16.0.zip
macOS Binary (x86_64) lefser_1.16.0.tgz
macOS Binary (arm64) lefser_1.15.11.tgz
Source Repository git clone https://git.bioconductor.org/packages/lefser
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/lefser
Bioc Package Browser https://code.bioconductor.org/browse/lefser/
Package Short Url https://bioconductor.org/packages/lefser/
Package Downloads Report Download Stats