DOI: 10.18129/B9.bioc.GOTHiC    

This is the development version of GOTHiC; for the stable release version, see GOTHiC.

Binomial test for Hi-C data analysis

Bioconductor version: Development (3.8)

This is a Hi-C analysis package using a cumulative binomial test to detect interactions between distal genomic loci that have significantly more reads than expected by chance in Hi-C experiments. It takes mapped paired NGS reads as input and gives back the list of significant interactions for a given bin size in the genome.

Author: Borbala Mifsud and Robert Sugar

Maintainer: Borbala Mifsud <b.mifsud at>

Citation (from within R, enter citation("GOTHiC")):


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biocViews Epigenetics, HiC, Preprocessing, Sequencing, Software
Version 1.17.0
In Bioconductor since BioC 2.14 (R-3.1) (4 years)
License GPL-3
Depends R (>= 2.15.1), methods, utils, GenomicRanges, Biostrings, BSgenome, data.table
Imports BiocGenerics, S4Vectors(>= 0.9.38), IRanges, Rsamtools, ShortRead, rtracklayer, ggplot2
Suggests HiCDataLymphoblast
Enhances parallel
Depends On Me
Imports Me
Suggests Me HiCDataLymphoblast
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Source Package GOTHiC_1.17.0.tar.gz
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