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CHETAH

This is the development version of CHETAH; for the stable release version, see CHETAH.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9

Fast and accurate scRNA-seq cell type identification


Bioconductor version: Development (3.24)

CHETAH (CHaracterization of cEll Types Aided by Hierarchical classification) is an accurate, selective and fast scRNA-seq classifier. Classification is guided by a reference dataset, preferentially also a scRNA-seq dataset. By hierarchical clustering of the reference data, CHETAH creates a classification tree that enables a step-wise, top-to-bottom classification. Using a novel stopping rule, CHETAH classifies the input cells to the cell types of the references and to "intermediate types": more general classifications that ended in an intermediate node of the tree.

Author: Jurrian de Kanter [aut, cre], Philip Lijnzaad [aut]

Maintainer: Jurrian de Kanter <jurriandekanter at gmail.com>

Citation (from within R, enter citation("CHETAH")):

Jurrian de Kanter, Philip Lijnzaad. CHETAH: Fast and accurate scRNA-seq cell type identification. doi:10.18129/B9.bioc.CHETAH, R package version 1.29.0, https://bioconductor.org/packages/CHETAH.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("CHETAH")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("CHETAH")
Introduction to the CHETAH package HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews Classification, Clustering, GeneExpression, ImmunoOncology, RNASeq, SingleCell, Software
Version1.29.0
In Bioconductor sinceBioC 3.9 (R-3.6) (7.5 years)
License file LICENSE
Depends R (>= 4.2), ggplot2, SingleCellExperiment
Imports shiny, plotly, pheatmap, bioDist, dendextend, cowplot, corrplot, grDevices, stats, graphics, reshape2, S4Vectors, SummarizedExperiment
System Requirements
URLhttps://github.com/jdekanter/CHETAH
Bug Reportshttps://github.com/jdekanter/CHETAH
See More
Suggests knitr, rmarkdown, Matrix, testthat, vdiffr
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package CHETAH_1.29.0.tar.gz
Windows Binary (x86_64) CHETAH_1.29.0.zip
macOS Binary (big-sur-x86_64) CHETAH_1.29.0.tgz
macOS Binary (sonoma-arm64) CHETAH_1.29.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/CHETAH
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/CHETAH
Package Short Url https://bioconductor.org/packages/CHETAH/
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