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topconfects

This is the released version of topconfects; for the devel version, see topconfects.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9

Top Confident Effect Sizes


Bioconductor version: Release (3.23)

Rank results by confident effect sizes, while maintaining False Discovery Rate and False Coverage-statement Rate control. Topconfects is an alternative presentation of TREAT results with improved usability, eliminating p-values and instead providing confidence bounds. The main application is differential gene expression analysis, providing genes ranked in order of confident log2 fold change, but it can be applied to any collection of effect sizes with associated standard errors.

Author: Paul Harrison [aut, cre] ORCID iD ORCID: 0000-0002-3980-268X

Maintainer: Paul Harrison <paul.harrison at monash.edu>

Citation (from within R, enter citation("topconfects")):

Paul Harrison. topconfects: Top Confident Effect Sizes. doi:10.18129/B9.bioc.topconfects, R package version 1.28.0, https://bioconductor.org/packages/topconfects.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("topconfects")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("topconfects")
An overview of topconfects HTML R Script
Confident fold change HTML R Script
Reference ManualPDF
NEWSText
LICENSEText

Details

biocViews DifferentialExpression, GeneExpression, MultipleComparison, RNASeq, Regression, Software, Transcriptomics, mRNAMicroarray
Version1.28.0
In Bioconductor sinceBioC 3.9 (R-3.6) (7.5 years)
License LGPL-2.1 | file LICENSE
Depends R (>= 3.6.0)
Imports methods, utils, stats, assertthat, ggplot2, scales, grid, grDevices
System Requirements
URLhttps://github.com/pfh/topconfects
Bug Reportshttps://github.com/pfh/topconfects/issues
See More
Suggests limma, edgeR, statmod, DESeq2, ashr, NBPSeq, dplyr, testthat, reshape2, tidyr, readr, org.At.tair.db, AnnotationDbi, knitr, rmarkdown, BiocStyle
Linking To
Enhances
Depends On Me
Imports Me GeoTcgaData, weitrix
Suggests Me
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package topconfects_1.28.0.tar.gz
Windows Binary (x86_64) topconfects_1.28.0.zip
macOS Binary (big-sur-x86_64) topconfects_1.28.0.tgz
macOS Binary (sonoma-arm64) topconfects_1.28.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/topconfects
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/topconfects
Package Short Url https://bioconductor.org/packages/topconfects/
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