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muscat

This is the released version of muscat; for the devel version, see muscat.

All versions 3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10

Multi-sample multi-group scRNA-seq data analysis tools


Bioconductor version: Release (3.23)

`muscat` provides various methods and visualization tools for DS analysis in multi-sample, multi-group, multi-(cell-)subpopulation scRNA-seq data, including cell-level mixed models and methods based on aggregated “pseudobulk” data, as well as a flexible simulation platform that mimics both single and multi-sample scRNA-seq data.

Author: Helena L. Crowell [aut, cre] ORCID iD ORCID: 0000-0002-4801-1767 , Pierre-Luc Germain [aut], Charlotte Soneson [aut], Anthony Sonrel [aut], Jeroen Gilis [aut], Davide Risso [aut], Lieven Clement [aut], Mark D. Robinson [aut, fnd]

Maintainer: Helena L. Crowell <helena at crowell.eu>

Citation (from within R, enter citation("muscat")):

Helena L. Crowell, Pierre-Luc Germain, Charlotte Soneson, Anthony Sonrel, Jeroen Gilis, Davide Risso, Lieven Clement, Mark D. Robinson. muscat: Multi-sample multi-group scRNA-seq data analysis tools. doi:10.18129/B9.bioc.muscat, R package version 1.26.0, https://bioconductor.org/packages/muscat.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("muscat")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("muscat")
"1. DS analysis" HTML R Script
"4. Increasing power with bulk-based hypothesis weighing" HTML R Script
"3. Differential detection" HTML R Script
"2. Data simulation" HTML R Script
Reference ManualPDF
NEWSText

Details

biocViews DifferentialExpression, ImmunoOncology, Sequencing, SingleCell, Software, StatisticalMethod, Visualization
Version1.26.0
In Bioconductor sinceBioC 3.10 (R-3.6) (7 years)
License GPL-3
Depends R (>= 4.5)
Imports BiocParallel, blme, ComplexHeatmap, dplyr, edgeR, ggplot2, glmmTMB, grDevices, grid, limma, lmerTest, lme4, Matrix, MatrixGenerics, matrixStats, methods, progress, rlang, S4Vectors, scales, scater, scuttle, stats, SingleCellExperiment, SummarizedExperiment, variancePartition
System Requirements
URLhttps://github.com/HelenaLC/muscat
Bug Reportshttps://github.com/HelenaLC/muscat/issues
See More
Suggests BiocStyle, countsimQC, DESeq2, AnnotationHub, ExperimentHub, iCOBRA, IHW, knitr, patchwork, phylogram, RColorBrewer, reshape2, rmarkdown, sctransform, statmod, stageR, testthat, tidyr, UpSetR
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me crumblr, DeeDeeExperiment, dreamlet, muscData
Links To Me
Build Report Build Report, r-universe

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package muscat_1.26.0.tar.gz
Windows Binary (x86_64) muscat_1.26.0.zip
macOS Binary (big-sur-x86_64) muscat_1.26.0.tgz
macOS Binary (sonoma-arm64) muscat_1.26.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/muscat
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/muscat
Package Short Url https://bioconductor.org/packages/muscat/
Package Downloads ReportDownload Stats