To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("synlet")

In most cases, you don't need to download the package archive at all.

synlet

DOI: 10.18129/B9.bioc.synlet    

This is the development version of synlet; for the stable release version, see synlet.

Hits Selection for Synthetic Lethal RNAi Screen Data

Bioconductor version: Development (3.6)

Select hits from synthetic lethal RNAi screen data. For example, there are two identical celllines except one gene is knocked-down in one cellline. The interest is to find genes that lead to stronger lethal effect when they are knocked-down further by siRNA. Quality control and various visualisation tools are implemented. Four different algorithms could be used to pick up the interesting hits. This package is designed based on 384 wells plates, but may apply to other platforms with proper configuration.

Author: Chunxuan Shao <c.shao at dkfz.de>

Maintainer: Chunxuan Shao <c.shao at dkfz.de>

Citation (from within R, enter citation("synlet")):

Installation

To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("synlet")

Documentation

HTML R Script A working Demo for synlet
PDF   Reference Manual
Text   NEWS

Details

biocViews CellBasedAssays, FeatureExtraction, Preprocessing, QualityControl, Software, Visualization
Version 1.7.0
In Bioconductor since BioC 3.2 (R-3.2) (2 years)
License GPL-3
Depends R (>= 3.2.0), ggplot2
Imports doBy, dplyr, grid, magrittr, RColorBrewer, RankProd, reshape2
LinkingTo
Suggests knitr, testthat
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package synlet_1.7.0.tar.gz
Windows Binary synlet_1.7.0.zip
Mac OS X 10.11 (El Capitan) synlet_1.7.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/synlet
Package Short Url http://bioconductor.org/packages/synlet/
Package Downloads Report Download Stats

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