DOI: 10.18129/B9.bioc.prebs  

This is the development version of prebs; for the stable release version, see prebs.

Probe region expression estimation for RNA-seq data for improved microarray comparability

Bioconductor version: Development (3.18)

The prebs package aims at making RNA-sequencing (RNA-seq) data more comparable to microarray data. The comparability is achieved by summarizing sequencing-based expressions of probe regions using a modified version of RMA algorithm. The pipeline takes mapped reads in BAM format as an input and produces either gene expressions or original microarray probe set expressions as an output.

Author: Karolis Uziela and Antti Honkela

Maintainer: Karolis Uziela <karolis.uziela at>

Citation (from within R, enter citation("prebs")):


To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))

# The following initializes usage of Bioc devel


For older versions of R, please refer to the appropriate Bioconductor release.


PDF   Reference Manual


biocViews GeneExpression, ImmunoOncology, Microarray, Preprocessing, RNASeq, Sequencing, Software
Version 1.41.0
In Bioconductor since BioC 2.12 (R-3.0) (10 years)
License Artistic-2.0
Depends R (>= 2.14.0), GenomicAlignments, affy, RPA
Imports parallel, methods, stats, GenomicRanges(>= 1.13.3), IRanges, Biobase, GenomeInfoDb, S4Vectors
Suggests prebsdata, hgu133plus2cdf, hgu133plus2probe
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary
macOS Binary (x86_64) prebs_1.41.0.tgz
macOS Binary (arm64)
Source Repository git clone
Source Repository (Developer Access) git clone
Bioc Package Browser
Package Short Url
Package Downloads Report Download Stats

Documentation »


R / CRAN packages and documentation

Support »

Please read the posting guide. Post questions about Bioconductor to one of the following locations: