NBSplice

DOI: 10.18129/B9.bioc.NBSplice    

Negative Binomial Models to detect Differential Splicing

Bioconductor version: Release (3.8)

The package proposes a differential splicing evaluation method based on isoform quantification. It applies generalized linear models with negative binomial distribution to infer changes in isoform relative expression.

Author: Gabriela A. Merino and Elmer A. Fernandez

Maintainer: Gabriela Merino <merino.gabriela33 at gmail.com>

Citation (from within R, enter citation("NBSplice")):

Installation

To install this package, start R (version "3.5") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")
BiocManager::install("NBSplice", version = "3.8")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("NBSplice")

 

HTML R Script NBSplice-vignette
PDF   Reference Manual
Text   NEWS

Details

biocViews AlternativeSplicing, DifferentialExpression, DifferentialSplicing, RNASeq, Regression, Software, StatisticalMethod
Version 1.0.0
License GPL (>=2)
Depends R (>= 3.5), methods
Imports edgeR, stats, MASS, car, mppa, BiocParallel, ggplot2, reshape2
LinkingTo
Suggests knitr, RUnit, BiocGenerics
SystemRequirements
Enhances
URL http://www.bdmg.com.ar
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package NBSplice_1.0.0.tar.gz
Windows Binary NBSplice_1.0.0.zip
Mac OS X 10.11 (El Capitan) NBSplice_1.0.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/NBSplice
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/NBSplice
Package Short Url http://bioconductor.org/packages/NBSplice/
Package Downloads Report Download Stats

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