DOI: 10.18129/B9.bioc.SEPIRA    

This is the development version of SEPIRA; for the stable release version, see SEPIRA.

Systems EPigenomics Inference of Regulatory Activity

Bioconductor version: Development (3.9)

SEPIRA (Systems EPigenomics Inference of Regulatory Activity) is an algorithm that infers sample-specific transcription factor activity from the genome-wide expression or DNA methylation profile of the sample.

Author: Yuting Chen [aut, cre], Andrew Teschendorff [aut]

Maintainer: Yuting Chen <cytwarmmay at>

Citation (from within R, enter citation("SEPIRA")):


To install this package, start R (version "3.6") and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
BiocManager::install("SEPIRA", version = "3.9")

For older versions of R, please refer to the appropriate Bioconductor release.


To view documentation for the version of this package installed in your system, start R and enter:



HTML R Script Introduction to `SEPIRA`
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biocViews GeneExpression, GeneRegulation, GeneTarget, Network, NetworkInference, Software, Transcription
Version 1.3.0
License GPL-3
Depends R (>= 3.5.0)
Imports limma(>= 3.32.5), corpcor (>= 1.6.9), parallel (>= 3.3.1), stats
Suggests knitr, rmarkdown, testthat, igraph
Depends On Me
Imports Me
Suggests Me
Links To Me
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Source Package SEPIRA_1.3.0.tar.gz
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Mac OS X 10.11 (El Capitan) SEPIRA_1.3.0.tgz
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