DOI: 10.18129/B9.bioc.MAGeCKFlute    

This is the development version of MAGeCKFlute; for the stable release version, see MAGeCKFlute.

Integrative analysis pipeline for pooled CRISPR functional genetic screens

Bioconductor version: Development (3.11)

MAGeCKFlute is designed for analyzing CRISPR screenings. It takes gene summary file returned by MAGeCK, as input, and surports quality control, normalization, and screen hit identification in the CRISPR screen. Furthermore, for identified hits, customized functional enrichment analysis will be done on biological pathways, protein complex and other molecular customized signatures.

Author: Wubing Zhang, Feizhen Wu, Binbin Wang

Maintainer: Wubing Zhang<Watson5bZhang at>

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biocViews BatchEffect, CRISPR, FunctionalGenomics, GeneSetEnrichment, GeneTarget, KEGG, Normalization, Pathways, PooledScreens, QualityControl, Software, Visualization
Version 1.7.1
In Bioconductor since BioC 3.7 (R-3.5) (2 years)
License GPL (>=3)
Depends R (>= 3.5)
Imports clusterProfiler, DOSE, enrichplot, gridExtra, pathview, biomaRt, sva, ggsci, ggplot2, ggrepel, ggpubr, data.table, pheatmap, png, grDevices, grid, stats, utils, dendextend, scales, Biobase, GO.db
Suggests knitr, testthat
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Imports Me SpidermiR
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