June 15, 2017

Road map

  • use cases
  • user interface concepts
  • cluster analysis components
    • primitive sensitivity analysis
  • classifier components
    • role of metapackages like caret/mlr/MLInterfaces

Use case 1: transcript profiles to distinguish tissue source

  • illumina bodymap in GEO
  • another application: adequacy of mouse models of human biology

Species and organ of origin: microarrays and orthologues (McCall et al., NAR 2012)

Species, organ of origin, and batch: RNA-seq and orthologues (Lin et al., PNAS 2014)