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BaalChIP

This is the development version of BaalChIP; for the stable release version, see BaalChIP.

All Bioconductor versions of BaalChIP

3.24 (devel), 3.23 (release), 3.22, 3.21, 3.20, 3.19, 3.18, 3.17, 3.16, 3.15, 3.14, 3.13, 3.12, 3.11, 3.10, 3.9, 3.8, 3.7, 3.6, 3.5, 3.4

BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes

Bioconductor version: 3.24 · Package version: 1.39.0

The package offers functions to process multiple ChIP-seq BAM files and detect allele-specific events. Computes allele counts at individual variants (SNPs/SNVs), implements extensive QC steps to remove problematic variants, and utilizes a bayesian framework to identify statistically significant allele- specific events. BaalChIP is able to account for copy number differences between the two alleles, a known phenotypical feature of cancer samples.

Author: Ines de Santiago, Wei Liu, Ke Yuan, Martin O'Reilly, Chandra SR Chilamakuri, Bruce Ponder, Kerstin Meyer, Florian Markowetz

Maintainer: Ines de Santiago <inesdesantiago at gmail.com>

DOI: 10.18129/B9.bioc.BaalChIP

Citation

From within R, enter citation("BaalChIP"):

Ines de Santiago, Wei Liu, Ke Yuan, Martin O'Reilly, Chandra SR Chilamakuri, Bruce Ponder, Kerstin Meyer, Florian Markowetz. BaalChIP: BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes. doi:10.18129/B9.bioc.BaalChIP, R package version 1.39.0, https://bioconductor.org/packages/BaalChIP.

Generated from the package metadata; it may differ from the package's own citation.

Installation

To install this package, start R (version "4.6") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

## The following initializes the development version of Bioconductor
BiocManager::install(version = "devel")

BiocManager::install("BaalChIP")

For older versions of R, please refer to the appropriate Bioconductor release.

Details

Version1.39.0
LicenseArtistic-2.0
Last updated2026-04-28
In Bioconductor sinceBioC 3.4 (R-3.3) (9 years)
Downloads rank1297 of 2,456
Source branchdevel
Build report Bioconductor build system, r-universe
biocViewsBayesian, ChIPSeq, Sequencing, Software
Package Short Url https://bioconductor.org/packages/BaalChIP/

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("BaalChIP")
BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes HTML R Script
Reference ManualPDF
NEWSText

Download

Follow the installation instructions to use this package in your R session.

Source packageBaalChIP_1.39.0.tar.gz
Windows binary (x86_64)BaalChIP_1.39.0.zip
macOS binary (arm64)BaalChIP_1.39.0.tgz
macOS binary (x86_64)BaalChIP_1.39.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/BaalChIP
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/BaalChIP
Package Downloads ReportDownload Stats
Dependencies

Depends: R (>= 3.3.1), GenomicRanges, IRanges, Rsamtools

Imports: GenomicAlignments, GenomeInfoDb, doParallel, parallel, doBy, reshape2, scales, coda, foreach, ggplot2, methods, utils, graphics, stats

Suggests: RUnit, BiocGenerics, knitr, rmarkdown, BiocStyle